Case Report

Vol. 18 No. 1 (2014): Endocrinology Research and Practice
DOI: https://doi.org/10.4274/tjem.2290

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Published: Mar 1, 2014
Keywords:
Anti-T4, anti-T3, discordant thyroid function tests

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Gülşah Elbüken
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Züleyha Karaca
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Fatih Tanrıverdi
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Kürşad Ünlühizarcı
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Samuel Refetoff
The University of Chicago, Department of Medicine and Pediatrics and the Committee on Genetics, Chicago, USA
Fahrettin Keleştimur
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey

Circulating Antibodies to T4 Causing Discordant Tests of Thyroid Function: A Case Report

Main Article Content

Gülşah Elbüken
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Züleyha Karaca
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Fatih Tanrıverdi
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Kürşad Ünlühizarcı
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Samuel Refetoff
The University of Chicago, Department of Medicine and Pediatrics and the Committee on Genetics, Chicago, USA
Fahrettin Keleştimur
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey

Abstract

ABSTRACT



The presence of elevated free thyroxine (fT4) hormone level with non-suppressed thyroid-stimulating hormone (TSH) level is called as “inappropriate secretion of TSH’’. TSH-secreting adenoma, resistance to thyroid hormone (RTH), iodothyronine deiodinase defect or false elevation of measured free serum T4 as in familial dysalbuminemic hyperthyroxinemia (FDH) and the presence of autoantibodies to T4 may be the cause of this entity. We report a case that presented with high serum fT4 and TSH levels associated with autoantibodies to T4.



 


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