Original Article

Vol. 18 No. 4 (2014): Endocrinology Research and Practice
DOI: https://doi.org/10.4274/tjem.2556

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Published: Dec 1, 2014
Keywords:
Salivary cortisol, enzymeimmunoassay, electrochemiluminescence, healthy subjects, HPA axis

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Gülşah Elbüken
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Kader Köse
Erciyes University Faculty of Medicine, Department of Biochemistry, Kayseri, Turkey
Züleyha Karaca
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Fatih Tanrıverdi
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Kürşad Ünlühizarcı
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Gökmen Zararsız
Erciyes University Faculty of Medicine, Department of Biostatistics, Kayseri, Turkey
Fahrettin Keleştimur
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey

Comparison of Electrochemiluminescence and Enzyme Immunoassay Methods for the Measurement of Salivary Cortisol

Main Article Content

Gülşah Elbüken
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Kader Köse
Erciyes University Faculty of Medicine, Department of Biochemistry, Kayseri, Turkey
Züleyha Karaca
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Fatih Tanrıverdi
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Kürşad Ünlühizarcı
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey
Gökmen Zararsız
Erciyes University Faculty of Medicine, Department of Biostatistics, Kayseri, Turkey
Fahrettin Keleştimur
Erciyes University Faculty of Medicine, Department of Endocrinology and Metabolism, Kayseri, Turkey

Abstract

ABSTRACT



Purpose: The aim of the study was to compare electrochemiluminescence (ECL) and enzyme immunoassay (EI) methods for the measurement of salivary cortisol (SC).

Material and Method: SC levels in 20 healthy subjects were measured by two different methods (EI and ECL).

Results: The results obtained from EI and ECL methods were found to be significantly correlated.

Discussion: Measuring SC by ECL method is faster and easier than EI in routine practice. Therefore, SC measured by ECL rather than EI may be used as a marker of hypothalamic-pituitary-adrenal (HPA) axis function.



 



 


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